• Bone pain or bones that break easily
• Nausea, vomiting, confusion, or feeling more thirsty than usual
• Feeling more weak, tired, or short of breath than usual
• Blurry vision
• Numbness, tingling, or weakness in the chest, lower back, or legs
• Getting sick more easily
• Losing weight without trying to

All of these symptoms can also be caused by conditions that are not multiple myeloma. But if you have these symptoms, let your doctor or nurse know.

Sometimes, symptoms of multiple myeloma can be a medical emergency. For example, it is an emergency if multiple myeloma cells or pieces of broken bone push down on a person's spinal cord. The spinal cord is the group of nerves that runs down a person’s back. See a doctor immediately if you have:

• Severe back pain
• Weakness, numbness, or tingling in the legs
• No control over your bladder or bowel (that is a new problem)

Test for multiple myeloma — the doctor or nurse will do an exam and tests. Tests can include:

• Blood or urine tests
• Bone marrow biopsy – A doctor will take a very small sample of the bone marrow. Another doctor will look at the sample under a microscope to see if cancer cells are present.
• X-ray or other imaging tests – Imaging tests create pictures of the inside of the body.

Multiple myeloma treatment — People with multiple myeloma often have one or more of the following treatments:

• “Watch and wait” – Some people have a condition called “smoldering myeloma” before they get multiple myeloma. These people do not have any symptoms and might not receive treatment right away. But their doctor does follow them. When they start to have symptoms, they will have active treatment.
• Chemotherapy – Chemotherapy is the term doctors use to describe a group of medicines that kill cancer cells.
• Steroid medicines – These medicines can kill cancer cells and slow cancer growth. (These steroids are not the same steroids that athletes take to build muscle.)
• Medicines called “immune modulating medicines” – These medicines stop the cancer from growing.
• Bone marrow transplant – The bone marrow makes blood cells, including white blood cells. During a bone marrow transplant, a doctor removes some bone marrow from the body. Then, the person gets medicines called “chemotherapy.” These medicines are usually used to kill cancer cells, but they also kill bone marrow cells. After chemotherapy, the doctor puts the bone marrow back into the person’s body.

People with multiple myeloma also have treatment for any symptoms they have. For example, doctors might treat bone symptoms with pain medicines, medicines to stop bone loss, or radiation therapy. Radiation can kill cancer cells.

After treatment, you will be checked every so often to see if the cancer comes back. Treatment does not usually cure the disease, but it can reduce symptoms and help people live longer. Follow-up tests can include blood tests, urine tests, imaging tests, or bone marrow biopsy.